Fig. 4
From: Exposure to nonanoic acid alters small intestinal neuroendocrine tumor phenotype
Effects of nonanoic acid in GOT1. (A) Transcripts that were significantly upregulated (p < 0.05) in response to nonanoic acid (Na) treatment in GOT1 cells. Arrows denote transcripts directly related to EC-cell hormone synthesis and secretion. (B) Secretion of serotonin measured by ELISA show serotonin secretion by GOT1 cells, but this was not affected by nonanoic acid exposure, symbols depict individual values, line depicts mean, and bars depict standard deviation, ***=p < 0,001. (C) Somatostatin-analog (SSA) did not affect the metabolic activity of GOT1 cells when treated with nonanoic acid (control = DMSO vehicle), symbols depict individual values, line depict mean, and bars depict standard deviation