Fig. 9
From: A novel cuproptosis-related gene signature to predict prognosis in Glioma
Overexpression of miR-606 inhibits the glycolysis and proliferation of GBM cells; knockdown of FDX1 inhibits the glycolysis and proliferation of GBM cells. A ECAR assays were used to detect the effect of miR-606 overexpression on the extracellular acidification rate in U251 and U373 cells. Data represent means ± SD (n = 3, each group). B-D The effect of miR-606 overexpression on lactate production, glucose consumption and cell proliferation were measured in U251 and U373 cells. Data represent means ± SD (n = 3, each group), **P < 0.01, compared with miR-606( +)NC group. E The effect of knockdown FDX1 on ECAR in U251 and U373 cells. Data represent means ± SD (n = 3, each group). F–H The effect of knockdown of FDX1 on lactate production, glucose consumption and cell proliferation were measured in U251 and U373 cells. Data represent means ± SD (n = 3, each group), **P < 0.01, compared with FDX1(-)NC group