Table 2 Univariate and multivariate analyses of influencing factors of prognosis

Initial PSA level

0.820

1.020

0.863

1.204

0.157

0.862

0.701

1.059

Initial stage (M0 vs M1)

0.091

0.776

0.578

1.042

0.469

0.876

0.611

1.254

Gleason score (8–10 vs 6–7)

0.848

1.034

0.737

1.450

0.550

0.897

0.629

1.280

Time to CRPC

 < 0.001

0.434

0.304

0.621

0.001

0.521

0.349

0.776

Chemotherapy (yes vs no)

 < 0.001

2.300

1.731

3.057

0.001

1.683

1.232

2.300

Age at baseline (years)

0.600

0.995

0.975

1.015

0.250

1.012

0.992

1.032

PSA level at baseline

 < 0.001

1.958

1.680

2.282

 < 0.001

1.439

1.179

1.755

ALP level at baseline

 < 0.001

5.138

3.509

7.524

0.019

1.827

1.102

3.028

LDH level at baseline

 < 0.001

45.886

23.15

90.953

 < 0.001

12.123

5.343

27.51