Fig. 3
From: NPAS2 promotes aerobic glycolysis and tumor growth in prostate cancer through HIF-1A signaling
NPAS2 knockdown inhibits PCa tumor growth in vivo
(A)Â Subcutaneous xenograft model for PC-3 cells treated as indicated and dissected tumors from sacrificed mice were shown
(B) Weight of tumors in nude mice
(C) Tumor volume changes curve of nude mice
(D) HE staining, immunohistochemical staining of NPAS2, Ki67 and PCNA in nude mice tumors. Scale bar: 50 μm
(E) Comparison of Ki-67-positive cells in tumor tissues of nude mice xenograft model with different treatment as indicated
(F) Comparison of PCNA-positive cells in tumor tissues of nude mice xenograft model with different treatment as indicated. *P＜0.05; **P＜0.01