Table 4 Treatment-Related Adverse Events
Terms | All grades, n (%) | Grade1/2, n (%) | Grade3/4, n (%) |
|---|---|---|---|
Leukopenia | 17(56.7) | 15(50.0) | 2(6.7) |
Neutropenia | 17(56.7) | 13(43.3) | 4(13.3) |
Febrile neutropenia | 2(6.7) | - | 2(6.7) |
Thrombocytopenia | 8(26.7) | 8(26.7) | 0(0) |
Anemia | 17(56.7) | 16(53.3) | 1(3.3) |
Fatigue | 14(46.7) | 14(46.7) | 0(0) |
Anorexia | 11(36.7) | 11(36.7) | 0(0) |
Nausea | 9(30.0) | 9(30.0) | 0(0) |
Emesis | 8(26.7) | 8(26.7) | 0(0) |
Alopecia | 16(53.3) | 16(53.3) | 0(0) |
Diarrhea | 5(16.7) | 5(16.7) | 0(0) |
Elevated alanine aminotransferase | 11(36.7) | 10(33.3) | 1(3.3) |
Elevated aspartate aminotransferase | 12(40.0) | 11(36.7) | 1(3.3) |
Elevated alkaline phosphatase | 9(30.0) | 8(26.7) | 1(3.3) |
Elevated gamma-glutamyl transpeptidase | 8(26.7) | 7(23.3) | 1(3.3) |
Hyperbilirubinemia | 3(10.0) | 2(6.7) | 1(3.3) |
Hyperglycemia | 6(20.0) | 6(20.0) | 0(0) |
Hyponatremia | 6(20.0) | 6(20.0) | 0(0) |
Hypokalemia | 7(23.3) | 7(23.3) | 0(0) |
Hypermagnesemia | 7(23.3) | 7(23.3) | 0(0) |
Hyperphosphatemia | 2(6.7) | 2(6.7) | 0(0) |
Hypercalcemia | 1(3.3) | 1(3.3) | 0(0) |
Hypocalcemia | 7(23.3) | 7(23.3) | 0(0) |
Hypothyroidism | 11(36.7) | 11(36.7) | 0(0) |
Proteinuria | 11(36.7) | 10(33.3) | 1(3.3) |
Hypertension | 5(16.7) | 5(16.7) | 0(0) |
Rash | 1(3.3) | 1(3.3) | 0(0) |
Immune pneumonia | 1(3.3) | 1(3.3) | 0(0) |
Cholinergic syndrome | 2(6.7) | 2(6.7) | 0(0) |