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Table 1 Demographics and baseline characteristics

From: Sintilimab Plus Apatinib and Chemotherapy as Second‑/Third-Line treatment for Advanced Gastric or Gastroesophageal Junction Adenocarcinoma: a prospective, Single-Arm, phase II trial

Characteristic

Patients, n (%)

Age, years, median (range)

59(28–73)

Sex

 

 Male

 Female

23(76.7)

7(23.3)

ECOG PS*

 

 0

 1

 2

4(13.3)

25(83.3)

1(3.3)

Primary tumor sites

 

 Lower esophagus

 Cardiac and gastric fundus

 Gastric body

 Gastric antrum

1(3.3)

7(23.3)

13(43.3)

9(30.0)

Cancer grading

 

 G1

 G2

 G3

0(0)

5(16.7)

25(83.3)

Lauren typing

 

 Intestinal type

 Diffuse type

 Mixed type or unknown

9(30.0)

14(46.7)

7(23.3)

Metastatic sites

 

 Lymph node

 Peritoneum

 Liver

 Bone

 Lung

19(63.3)

9(30.0)

8(26.7)

2(6.7)

1(3.3)

Prior treatment regimens

 

 First-line

 Second-line

 Platinum and Fluorouracil

 Taxanes

25(83.3)

5(16.7)

29(96.7)

7(23.3)

MMR/MSI*

 

 MMR deficient

 MMR proficient

0(0)

30(100.0)

HER2*

 

 0

 1+

 2+/FISH*(-)

22(73.3)

4(13.3)

4(13.3)

EBER*

 

 Negative

 Positive

30(100.0)

0(0)

  1. *ECOG PS: Eastern Cooperative Oncology Group Performance Status
  2. MMR: Mismatch Repair
  3. MSI: Microsatellite Instability
  4. HER2: Human Epidermal Growth Factor Receptor 2
  5. FISH: Fluorescence in Situ Hybridization
  6. EBER: Epstein-Barr virus-encoded RNA