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Table 2 GO enrichment annotations and associations for the gene network associated with increased tumor height; these processes collectively involve metabolic (anabolic and catabolic) processes

From: Construction of a radiogenomic association map of pancreatic ductal adenocarcinoma

GO term

Description

P-value

FDR q-value

Enrichment

GO:0004497

monooxygenase activity

3.61E-05

1.68E-01

3.35

GO:0099073

mitochondrion-derived vesicle

1.08E-04

2.12E-01

20.98

GO:1990247

N6-methyladenosine-containing RNA binding

1.60E-04

3.73E-01

11.99

GO:0046854

phosphatidylinositol phosphorylation

1.73E-04

1.00E+00

3.96

GO:0005839

proteasome core complex

1.83E-04

1.80E-01

6.62

GO:0055076

transition metal ion homeostasis

2.02E-04

1.00E+00

2.77

GO:0008654

phospholipid biosynthetic process

2.70E-04

1.00E+00

2.15

GO:0010499

proteasomal ubiquitin-independent protein catabolic process

3.38E-04

1.00E+00

5.99

GO:0009889

regulation of biosynthetic process

4.03E-04

1.00E+00

1.21

GO:0061734

parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

4.16E-04

1.00E+00

15.73

GO:0031326

regulation of cellular biosynthetic process

4.24E-04

9.33E-01

1.22

GO:0009952

anterior/posterior pattern specification

4.31E-04

8.29E-01

2.51

GO:0046486

glycerolipid metabolic process

4.65E-04

7.96E-01

1.86

GO:0016723

oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor

5.33E-04

8.29E-01

9.32

GO:0006650

glycerophospholipid metabolic process

5.56E-04

8.56E-01

1.93

GO:1900076

regulation of cellular response to insulin stimulus

5.70E-04

7.98E-01

3.2

GO:0006644

phospholipid metabolic process

5.88E-04

7.54E-01

1.84

GO:2000112

regulation of cellular macromolecule biosynthetic process

6.50E-04

7.69E-01

1.22

GO:0016722

oxidoreductase activity, oxidizing metal ions

6.84E-04

7.98E-01

6.56

GO:0003700

DNA-binding transcription factor activity

6.87E-04

6.41E-01

1.41

GO:0010556

regulation of macromolecule biosynthetic process

7.58E-04

8.33E-01

1.21

GO:0016712

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

7.85E-04

6.11E-01

4.45

GO:0046916

cellular transition metal ion homeostasis

8.32E-04

8.54E-01

2.75

GO:0046626

regulation of insulin receptor signaling pathway

8.39E-04

8.07E-01

3.28

GO:0098780

response to mitochondrial depolarisation

9.31E-04

8.43E-01

6.17

GO:0016705

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

9.42E-04

6.29E-01

2.35

GO:0045017

glycerolipid biosynthetic process

9.61E-04

8.22E-01

2.08

GO:0046906

tetrapyrrole binding

9.66E-04

5.64E-01

2.41

GO:0046474

glycerophospholipid biosynthetic process

9.80E-04

7.94E-01

2.12