Table 2 Effectiveness of colposcopy in distinguishing <LSIL from LSIL+
Study | TP | FP | FN | TN | Total | Sensitivity (95% CI) | Specificity (95% CI) |
|---|---|---|---|---|---|---|---|
Ghosh et al., 2014 [24] | 196 | 1705 | 32 | 533 | 2466 | 0.86 (0.81–0.90) | 0.24 (0.22–0.26) |
Spinillo et al., 2014 [28] | 432 | 1013 | 103 | 978 | 2526 | 0.81 (0.77–0.84) | 0.49 (0.47–0.51) |
Zhao et al., 2015 [30] | 70 | 449 | 16 | 1462 | 1997 | 0.81 (0.72–0.89) | 0.77 (0.75–0.78) |
Coronado et al., 2016 [22] | 38 | 123 | 3 | 279 | 443 | 0.93 (0.80–0.98) | 0.69 (0.65–0.74) |
Li et al., 2017 [8] | 90 | 195 | 9 | 231 | 525 | 0.91 (0.83–0.96) | 0.54 (0.49–0.59) |
Fan et al., 2018 [9] | 612 | 901 | 19 | 730 | 2262 | 0.97 (0.95–0.98) | 0.45 (0.42–0.47) |
Liu et al., 2018 [31] | 30 | 112 | 0 | 114 | 256 | 1.00 (0.88–1.00) | 0.50 (0.44–0.57) |
Ruan et al., 2020 [27] | 430 | 538 | 71 | 789 | 1828 | 0.86 (0.82–0.89) | 0.59 (0.57–0.62) |
Del Pino et al., 2021 [23] | 98 | 88 | 25 | 91 | 302 | 0.80 (0.71–0.86) | 0.51 (0.43–0.58) |
Li et al., 2021 [25] | 289 | 114 | 9 | 83 | 495 | 0.97 (0.94–0.99) | 0.42 (0.35–0.49) |
Liu et al., 2021 [26] | 160 | 328 | 10 | 489 | 987 | 0.94 (0.89–0.97) | 0.60 (0.56–0.63) |
Zhang et al., 2022 [33] | 603 | 878 | 12 | 345 | 1838 | 0.98 (0.97–0.99) | 0.28 (0.26–0.31) |
Maffini et al., 2022 [34] | 69 | 6 | 9 | 18 | 102 | 0.88 (0.79–0.95) | 0.75 (0.53–0.90) |
Wei et al., 2022 [29] | 1028 | 618 | 55 | 716 | 2417 | 0.95 (0.93–0.96) | 0.54 (0.51–0.56) |
Stuebs et al., 2022 [32] | 2397 | 1373 | 281 | 727 | 4778 | 0.90 (0.88–0.91) | 0.35 (0.33–0.37) |