Fig. 1

Relationship betweenFGFR4copy number and protein expression in ccRCC clinical specimens. A, Immunohistochemistry of ccRCC clinical specimens. Representative slide of the four-point scale evaluation shown (upper row), and staining characteristic of cancer and non-cancerous areas are shown in the lower panel. B, Comparison of FGFR4 expression among ccRCC clinical stages. Standardised staining score were estimated by regions (cancer, interstitial and vessel, normal area) and compared by clinical stage. C, Comparison between estimated FGFR4 copy number and FGFR4 protein expression. Each average value is shown (left) and the correlation diagram is shown (right). Abbreviations: FGFR4, fibroblast growth factor receptor 4; ccRCC, clear cell renal cell carcinoma