Table 2 Univariate and multivariate analyses of local control, progression-free survival, and overall survival
Local control | Progression-free survival | Overall survival | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | ||||||
Factors | No. of patients | P-value | Hazard ratio (95% CI) | P-value | No. of patients | P-value | Hazard ratio (95% CI) | P-value | P-value | Hazard ratio | P-value |
Age (years) | 0.719 | 0.988 | 0.441 | ||||||||
<68.7 | 56 | 30 | |||||||||
≥68.7 | 56 | 43 | |||||||||
PS | 0.708 | 0.008 | 0.187 | 0.002 | 2.62 | 0.021 | |||||
0 | 82 | 50 | (1.19-5.80) | ||||||||
1–2 | 30 | 23 | |||||||||
Sex | 0.142 | 0.427 | 0.089 | ||||||||
Male | 55 | 31 | |||||||||
Female | 57 | 42 | |||||||||
Smoking status | 0.002 | 6.80 | 0.024 | 0.040 | 0.303 | 0.092 | |||||
Current or previous | 40 | (1.84-54.71) | 35 | ||||||||
Never | 52 | 21 | |||||||||
Primary site | <0.001 | 1.3*109 | 0.012 | 0.553 | 0.186 | ||||||
Colorectum | 23 | (0-NC) | 16 | ||||||||
Others | 89 | 57 | |||||||||
Histology | 0.011 | 0.466 | 0.078 | 0.334 | |||||||
SCC | 47 | 33 | |||||||||
Adenocarcinoma | 41 | 26 | |||||||||
Sarcoma | 12 | 5 | |||||||||
Others | 12 | 9 | |||||||||
Tumor diameter | <0.001 | 0.071 | <0.001 | 4.23 | 0.002 | <0.001 | 3.78 | 0.018 | |||
<25 mm | 101 | 63 | (1.77-10.1) | (1.37-10.45) | |||||||
≥25 mm | 11 | 10 | |||||||||
Chemotherapy within 3 months before SABR | 0.246 | 0.650 | 0.575 | ||||||||
Yes | 29 | 22 | |||||||||
No | 83 | 51 | |||||||||
Numbers of SABR | 0.439 | 0.280 | 0.968 | ||||||||
1 location | 49 | 49 | |||||||||
2 or more locations | 63 | 24 | |||||||||
BED10 | 0.124 | 0.077 | 0.334 | ||||||||
<100 Gy | 17 | 9 | |||||||||
≥100 Gy | 95 | 64 | |||||||||