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Table 3 Large Scale Copy Number Changes

From: Somatic mutation landscape in a cohort of meningiomas that have undergone grade progression

FEATURE

Number Patients

Number tumours

% NF2 mutant

% NF2 mutation not detected

LOSS 1p

4

19

100%

0%

LOSS 10 (10, 10q)

6

21

100%

33%

LOSS 22.q

5

22

100%

17%

LOSS 9p

3

9

75%

17%

LOSS 2p

3

9

75%

0%

LOSS 3p or aberrant 3

3

12

75%

0%

LOSS 4p or aberrant 4

3

12

50%

0%

LOSS 14q

2

10

50%

0%

LOSS 18q

3

14

50%

17%

LOSS 5 (5, 5p, 5q)

3

10

50%

17%

LOSS 6q or aberrant 6

4

14

50%

33%

LOSS 11 (11p, 11q, 11, focal)

6

20

50%

67%

LOSS + GAIN 17q

2

6

0%

33%