Table 1 Distribution and comparison of clinical characteristics across the four LUAD metabolic subtypes

Age

3.866

0.276

  < = 60

41(34.17%)

24(23.08%)

41(32.28%)

45(33.09%)

  > 60

76(63.33%)

77(74.04%)

85(66.93%)

88(64.71%)

 NA

3(2.5%)

3(2.88%)

1(0.79%)

3(2.21%)

Sex

0.803

0.849

 Female

66(55%)

53(50.96%)

72(56.69%)

73(53.68%)

 Male

54(45%)

51(49.04%)

55(43.31%)

63(46.32%)

T_stage

0.513

0.916

 T1&T2

105(87.5%)

92(88.46%)

109(85.83%)

116(85.29%)

 T3&T4

14(11.67%)

12(11.54%)

17(13.39%)

19(14.96%)

 Tx

1(0.83%)

0(0)

1(0.79%)

1(0.79%)

N_stage

4.065

0.255

 N0

84(70%)

69(66.35%)

79(62.20%)

81(59.56%)

 N1&N2%N3

33(27.5%)

33(31.73%)

46(36.22%)

53(38.97%)

 Nx

3(2.5%)

2(1.92%)

2(1.57%)

2(1.47%)

M_stage

9.078

0.028

 M0

82(68.33%)

66(63.46%)

85(66.93%)

89(65.44%)

 M1

2(1.67%)

2(1.92%)

12(9.45%)

8(5.88%)

 Mx

36(30%)

36(34.62%)

30(23.62%)

39(28.68%)

TNM_stage

4.006

0.261

 I&II

97(80.8%)

84(80.77%)

94(74.01%)

99(72.79%)

 III&IV

20(16.7%)

20(19.23%)

29(22.83%)

36(26.47%)

 NA

3(2.5%)

0

4(3.15%)

1(0.74%)

New_Event_Type

9.835

0.132

 Distant Metastasis

13(10.83%)

27(25.96%)

16(12.60%)

16(11.76%)

 Locoregional Recurrence

18(15%)

9(8.65%)

15(11.81%)

14(10.29%)

 New Primary Tumor

3(2.5%)

3(2.88%)

1(0.79%)

4(2.94%)

 NA

86(71.67%)

75(72.12%)

95(74.80%)

102(75%)

Anatomic_neoplasm_subdivision

28.414

0.005

 R-Lower

18(15%)

17(16.35%)

31(24.41%)

27(19.85%)

 R-Middle

6(5%)

9(8.65%)

5(3.94%)

1(0.74%)

 R-Upper

35(29.17%)

36(34.62%)

46(36.22%)

53(38.97%)

 L-Lower

25(20.83%)

13(12.5%)

23(18.11%)

14(10.29%)

 L-Upper

33(27.5%)

27(25.96%)

16(12.60%)

38(27.94%)

 Others/NA

3(2.5%)

2(1.92%)

6(4.72%)

3(2.21%)

location_in_lung_parenchyma

2.889

0.409

 Peripheral Lung

29(24.17%)

30(28.85%)

28(22.05%)

31(22.79%)

 Central Lung

11(9.17%)

12(11.54%)

17(13.39%)

22(16.18%)

 NA

80(66.67%)

62(59.62%)

82(64.57%)

83(61.03%)