Fig. 6

ANRIL shRNA increased radiosensitivity in xenograft nude mice. Tumor volume was measured every 3 days. At 24 days after the local ionizing radiation, the mice were killed and the tumors were stripped. a Photographs of tumors in nude mice. b The tumor growth curve and (c) tumor weight of transplantation tumor of nude mice. d Tumor section was carried out for immunohistochemistry of Ki67 and Tunel. e–f Respective mean density of Ki67 and Tunel in tumor by quantitative analysis. g The protein levels of a panel of core factors in HR signaling were reduced in shANRIL group