Table 1 Clinical characteristics of patient population
characteristic | NMM (n=43) | MM (n=334) | P value |
|---|---|---|---|
Median age (range), years | 56 (34 -78) | 60.5 (26 - 91) | 0.01* |
Sex (male), (n, %) | 32 (74.42%) | 199 (59.58%) | 0.06 |
Median hemoglobin (range) (g/L) | 127 (81 - 162) | 89 (36 - 166) | < 0.0001* |
Median serum albumin (range) (g/L) | 37.60 (14.90 - 49.50) | 35.3 (14.10 - 51.60) | 0.99 |
Median serum LDH (range) (U/L) | 201 (86 - 426) | 190.5 (57 - 1867) | 0.20 |
Median serum calcium (range) (g/L) | 2.37 (2.13 - 2.78) | 2.47 (1.91-4.40) | 0.0003* |
Median serum creatinine (range) (g/L) | 84 (43 - 583) | 89 (36 - 1210) | 0.33 |
Median serum β2-M (range) (g/L) | 2.9 (1.44 - 14.53) | 5.37 (1.49 - 80) | < 0.0001* |
M protein isotype | Â | Â | 0.16 |
 IgG | 18 (41.86%) | 142 (42.51%) |  |
 IgA | 14 (32.56%) | 89 (26.65%) |  |
 Light chain | 7 (16.28%) | 70 (20.96%) |  |
 IgD&IgE | 0 | 21 (6.29%) |  |
 others | 4 (9.30%) | 12 (3.59%) |  |
Prior therapy | |||
 Auto-HSCT | 0 | 16 (4.79%) | 0.287 |
 BCMA CART trial | 0 | 13 (3.89%) | 0.383 |