Table 1 The Correlation Between TIPE3 Expression and Clinicopathological Features in CRC Patients
Characteristics | TIPE3 expression in Tumor tissues | p-value | TIPE3 expression in Adjacent normal tissues | p-value | ||
|---|---|---|---|---|---|---|
Low(n=34) | High(n=76) | Low(n=72) | High(n=38) | |||
Gender | ||||||
Male | 24 (70.6) | 46 (60.5) | 0.424 | 49 (68.1) | 21 (55.3) | 0.264 |
Fmale | 10 (29.4) | 30 (39.5) | 23 (31.9) | 17 (44.7) | ||
Lymph node metastasis | ||||||
Negative | 17 (50.0) | 42 (55.3) | 0.761 | 40 (55.6) | 19 (50.0) | 0.723 |
Postive | 17 (50.0) | 34 (44.7) | 32 (44.4) | 19 (50.0) | ||
Invasion | ||||||
I | 1 ( 2.9) | 0 ( 0.0) | 0.489 | 1 ( 1.4) | 0 ( 0.0) | 0.491 |
II | 4 (11.8) | 11 (14.5) | 12 (16.7) | 3 ( 7.9) | ||
III | 23 (67.6) | 50 (65.8) | 45 (62.5) | 28 (73.7) | ||
IV | 6 (17.6) | 15 (19.7) | 14 (19.4) | 7 (18.4) | ||
TNM | ||||||
T1 | 5 (14.7) | 11 (14.5) | 0.851 | 13 (18.1) | 3 ( 7.9) | 0.356 |
T2 | 12 (35.3) | 31 (40.8) | 27 (37.5) | 16 (42.1) | ||
T3 | 17 (50.0) | 34 (44.7) | 32 (44.4) | 19 (50.0) | ||
Grade | ||||||
Low | 4 (11.8) | 17 (22.4) | 0.395 | 13 (18.1) | 8 (21.1) | 0.727 |
Moderate | 29 (85.3) | 56 (73.7) | 57 (79.2) | 28 (73.7) | ||
High | 29 (85.3) | 56 (73.7) | 2 ( 2.8) | 2 ( 5.3) | ||
Location (%) | ||||||
Location (%) | 29 (85.3) | 56 (73.7) | 0.554 | 28 (38.9) | 17 (44.7) | 0.697 |
Colon | 22 (64.7) | 43 (56.6) | 44 (61.1) | 21 (55.3) | ||
Status (%) | ||||||
Survive | 29 (85.3) | 42 (55.3) | 0.005** | 56 (77.8) | 15 (39.5) | <0.001 |
Dead | 5 (14.7) | 34 (44.7) | 16 (22.2) | 23 (60.5) | ||
CEA | 5.61 [2.96, 20.33] | 3.70 [2.31, 7.77] | 0.078 | 3.80 [2.36, 7.93] | 4.96 [2.53, 14.77] | 0.343 |
CA-199 | 13.71 [9.12, 32.54] | 10.64 [6.11, 26.79] | 0.196 | 11.34 [6.91, 21.13] | 13.61 [6.26, 37.21] | 0.418 |
Age | 65.50 [57.25, 77.75] | 62.00 [53.75, 68.00] | 0.179 | 63.00 [56.50, 72.00] | 62.00 [53.25, 70.00] | 0.792 |
Survive Time | 64.00 [63.00, 64.75] | 63.00 [35.50, 64.00] | 0.006** | 64.00 [63.00, 64.00] | 56.00 [22.25, 63.00] | <0.001 |
WBC | 6.32 [4.88, 6.88] | 5.72 [4.64, 7.35] | 0.874 | 5.74 [4.56, 7.04] | 6.29 [4.91, 7.26] | 0.622 |
Neutrophil | 3.60 [2.95, 4.69] | 3.23 [2.75, 4.76] | 0.514 | 3.48 [2.80, 4.77] | 3.29 [2.80, 4.73] | 0.664 |
Lymphocyte | 1.46 [1.23, 1.87] | 1.48 [1.12, 1.95] | 0.828 | 1.40 [1.08, 1.77] | 1.66 [1.29, 2.17] | 0.011* |
Monocyte | 0.37 [0.30, 0.45] | 0.36 [0.28, 0.48] | 0.864 | 0.36 [0.28, 0.45] | 0.38 [0.28, 0.55] | 0.196 |
Hb | 131.00 [113.25, 137.00] | 125.50 [97.75, 132.25] | 0.113 | 127.50 [107.25, 134.00] | 122.50 [101.75, 131.50] | 0.336 |
PLT | 214.50 [171.50, 280.00] | 217.00 [171.00, 265.25] | 0.910 | 1218.00 [169.50, 266.25] | 196.00 [173.00, 270.50] | 0.797 |