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Table 4 Symptoms Influenced by Financial Toxicity Among Cancer Patients Taking Oral Chemotherapy at Home

From: Associations of financial toxicity with symptoms and unplanned healthcare utilization among cancer patients taking oral chemotherapy at home: a prospective observational study

Variables

Estimate

SE

Wald

p-value

95% CI

Dependent variable: Fatigue

 

Financial Toxicity (Estimate Severe=0)

 

 No/mild

-0.506

0.550

0.845

0.358

-1.584, 0.573

 Moderate

-0.746

0.353

4.461

0.035 *

-1.437, -0.054

Dependent variable: Disturbed sleep

 

Financial Toxicity (Estimate Severe=0)

 

 No/mild

-1.073

0.536

4.003

0.045 *

-2.124, -0.022

 Moderate

-1.073

0.346

9.597

0.002 **

-1.752, -0.394

Dependent variable: Distress (emotional)

 

Financial Toxicity (Estimate Severe=0)

 

 No/mild

-1.283

0.602

4.537

0.033 *

-2.463, -0.102

 Moderate

-0.867

0.354

6.012

0.014 *

-1.561, -0.174

Dependent variable: Lack of appetite

 

ECOG score (Estimate score 2 =0)

 

 0

-2.174

0.908

5.734

0.017 *

-3.953, -0.395

 1

-1.642

0.805

4.155

0.042 *

-3.220, -0.063

Financial Toxicity (EstimateSevere=0)

 

 No/mild

-0.590

0.539

1.196

0.274

-1.647, 0.467

 Moderate

-1.135

0.359

9.984

0.002 **

-1.840, -0.431

Dependent variable: mood interference

 

Age ( Estimate≥ 60y =0 )

 

 <45y

0.686

0.523

1.718

0.190

-0.340, 1.711

 ≥45, <60y

1.003

0.462

4.708

0.030 *

0.097, 1.909

Financial Toxicity (Estimate Severe=0)

 

 No/mild

-1.659

0.827

4.027

0.045 *

-3.280, -0.039

 Moderate

-0.644

0.390

2.734

0.098

-1.408, 0.120

Dependent variable: interference of relations with others

 

Financial Toxicity (Estimate Severe=0)

 

 No/mild

-2.200

1.080

4.150

0.042 *

-4.318, -0.083

 Moderate

-0.955

0.411

5.392

0.020 *

-1.761, -0.149

  1. SE, standard error; CI, confidence interval
  2. *: p < 0.05, **: p < 0.01, bold: significant result
  3. Level of Financial Toxicity: higher total score of the Comprehensive Score for Financial Toxicity (COST) indicates better financial well-being. COST ≥ 26 means no/mild financial toxicity, COST 14–25 means moderate financial toxicity, COST 0–13 means severe financial toxicity