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Table 4 Pregnancy outcomes

From: Cardiac and obstetric outcomes of pregnancies for women after cardiotoxic therapy in childhood: a single center observational study

 

Total (%*)

General population†

# of pregnancies (N = 39 women)

  

 1

8 (20.5)

 

 2

18 (46.2)

 

 3

9 (23.1)

 

 4

2 (5.1)

 

 5

1 (2.6)

 

 7

1 (2.6)

 

Outcome stratified by gestational age, weeks (N = 91 pregnancies)

  

 Live birth > 37 + 0

65 (71.4)

 

 Live birth 32 + 0 to 36 + 6

4 (4.4)

 

 Live birth 28 + 0 to 31 + 6

1 (1.1)

 

 Live birth 24 + 0 to 27 + 6

3 (3.3)

 

 Miscarriage < 12 + 0

14 (15.4)

 

 Miscarriage 12 + 0 to 15 + 6

0 (0.0)

 

 Intrauterine fetal demise > 16 + 0 to 23 + 6

3 (3.3)

 

 Abortion

1 (1.1)

 

Mode of birth (N = 73 live births)

  

 Spontaneous vaginal birth

55 (75.3).

P = 74.4%

 Assisted vaginal birth

7 (9.6).

P = 7.0%

 Caesarean section

11 (15.1).

P = 15.2%

Maternal outcome (N = 73 live births)

  

Hypertensive disorders during pregnancy

  

 None

63 (86.3)

 

 Pregnancy induced hypertension

8 (11.0)

P = 5.7%

 Pre-eclampsia

2 (2.7).

P = 0.5%

Diabetes

0 (0.0)

P = 4.0%

Postpartum hemorrhage > 1L

1 (1.4)

P = 6.5%

Endometritis postpartum, treated medically

1 (1.4)

P = 1.7%

Manual removal of retained placenta

3 (4.1)

 

Laparotomy for spontaneous lesion of uterine serosa

1 (1.1)

 

Fetal outcome (N = 73 live births)

  

Apgar < 7 at 5 minutes post-partum

2 (2.7)

P = 2.0%

Birthweight < p10 for gestational age

10 (13.7)

P = 10%

Preterm birth

8 (11.0)

P = 6.9%

Intra-uterine fetal death

0

P = 0.3%

Neonatal death‡

0

P = 0.2

Congenital disease§

1 (1.4%)

P = 1.0%

  1. * denominator is reported within brackets per category in left column. † Source: Dutch national perinatal registry (PERINED). ‡ defined as: death within 28 days post-partum. § Infant died four months after birth