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Table 2 FGFR3 mutation associated with immune cell densities

From: Characterisation of tumour-immune phenotypes and PD-L1 positivity in squamous bladder cancer

 

FGFR3 mutation

na

neg

pos

P-valueb

Immune cell markers:

 CD3

  ≤ 582.3/mm2

26

22

4

0.387

  > 582.3/mm2

36

33

3

 CD4

  ≤ 141.5/mm2

29

26

3

0.964

  > 141.5/mm2

28

25

3

 CD8

  ≤ 291.6/mm2

25

20

5

0.039

  > 291.6/mm2

32

31

1

 CD68

  ≤ 493.0/mm2

28

27

1

0.121

  > 493.0/mm2

32

27

5

 CD79A

  ≤ 85.9/mm2

30

24

6

0.036

  > 85.9/mm2

32

31

1

  CD163

  ≤ 462.1/mm2

32

27

5

0.307

  > 462.1mm2

28

26

2

 Perforin

  ≤ 9.0/mm2

17

13

4

0.022

  > 9.0/mm2

33

32

1

  1. aOnly patients with primary sq-BLCA were included; bPearson’s chi-square test; Significant P-values are marked in bold face. Please note: sample numbers may vary between analyses due to limitations of usable TMA cores depending on the staining