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Table 1 Clinico-pathological parameters associated with CD8 density

From: Characterisation of tumour-immune phenotypes and PD-L1 positivity in squamous bladder cancer

 

CD8 densityb

na

low

high

P-valuec

Parameter:

 Age at diagnosis

  < 68 years

50

23

27

0.616

  ≥ 68 years

53

27

26

 Gender

  male

48

24

24

0.852

  female

54

26

28

 Tumour subtype

  pure SCC

65

38

27

0.028

  mix SCC

41

15

26

 Histological tumour grade

  G1-G2

30

16

14

0.447

  G3-G4

71

32

39

 Tumour stage

  pT1-pT2

15

5

10

0.288

  pT3-pT4

83

40

43

 Nodal status

  pN0

62

29

33

0.597

  pN + 

20

8

12

 Lymphatic invasion

  L0

38

18

20

0.707

  L1

19

8

11

  1. aOnly patients with primary sq-BLCA were included; bdensity in cells / mm2; median value of the overall sample (291.6 / mm2) as cut-off for low and high density; cPearson's chi-square test; Significant P-values are marked in bold face. Please note: sample numbers may vary between analyses due to limitations of usable TMA cores depending on the staining