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Fig. 7 | BMC Cancer

Fig. 7

From: Histone methyltransferase SETD1A interacts with notch and promotes notch transactivation to augment ovarian cancer development

Fig. 7

Restoration of Notch1 in SETD1A-knockdown OV cells recovers cell proliferation, migration and invasion. A,B The cell viabilities of overexpression of Notch1 in SETD1A-knockdown SKOV3 A and Caov3 B cells analyzed by CCK-8 assays. Unpaired two-tailed t-test. Data are expressed as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. C,D The cell migration and invasion of overexpression of Notch1 in SETD1A-knockdown SKOV3 C and Caov3 D cells analyzed by transwell migration and invasion. Unpaired two-tailed t-test. Data are expressed as mean ± SD. **p < 0.01, ***p < 0.001. (the scale bar = 100 μm)

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BMC Cancer

ISSN: 1471-2407

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