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Fig. 2 | BMC Cancer

Fig. 2

From: Histone methyltransferase SETD1A interacts with notch and promotes notch transactivation to augment ovarian cancer development

Fig. 2

SETD1A promotes OV cell proliferation. A The protein levels of OV cells and epithelial cell analyzed by western blotting assays. B,C The protein levels of RMGI, OVCAR5, SKOV3 and Caov3 analyzed by western blotting assays. D The cell viabilities of SETD1A overexpression RMGI and OVCAR5 cells analyzed by CCK-8 assays. Unpaired two-tailed t-test. Data are expressed as mean ± SD.**p < 0.01, ***p < 0.001, ****p < 0.0001. E The cell viabilities of SETD1A knockdown SKOV3 and Caov3 cells analyzed by CCK-8 assays. Unpaired two-tailed t-test. Data are expressed as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. F The cell numbers of SETD1A overexpression RMGI and OVCAR5 cells counted by typan blue staining. Unpaired two-tailed t-test. Data are expressed as mean ± SD. **p < 0.01, ***p < 0.001, ****p < 0.0001. G The cell numbers of SETD1A knockdown SKOV3 and Caov3 cells analyzed by typan blue staining. Unpaired two-tailed t-test. Data are expressed as mean ± SD. **p < 0.01, ***p < 0.001, ****p < 0.0001

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BMC Cancer

ISSN: 1471-2407

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