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Table 2 Subgroup analysis of the association between ALI and overall and disease-free survival in patients with gastrointestinal neoplasms

From: The prognostic value of the advanced lung cancer inflammation index in patients with gastrointestinal malignancy

Variable

Included studies

Test of association

Test of heterogeneity

HR

95%CI

P value

Modal

I2

P value

Overall survival

 Study region

  China

10

1.694

1.316–2.180

 < 0.001

RE

84.3%

 < 0.001

  Japan

4

2.313

1.676–3.192

 < 0.001

RE

59.0%

0.063

  Other

2

2.444

1.696–3.523

 < 0.001

RE

0.0%

0.596

 Sample size

   ≤ 300

8

2.016

1.364–2.980

 < 0.001

RE

88.1%

 < 0.001

   > 300

8

1.777

1.448–2.182

 < 0.001

RE

58.9%

0.017

 Treatment

  Surgery

12

1.837

1.406–2.402

 < 0.001

RE

89.5%

 < 0.001

  Other

2

2.156

1.658–2.804

 < 0.001

RE

23.0%

0.253

 Cut-off

   > 30

9

1.839

1.320–2.564

 < 0.001

RE

87.3%

 < 0.001

   ≤ 30

5

2.086

1.627–2.674

 < 0.001

RE

45.5%

0.076

  Other

2

1.776

1.136–2.775

0.012

RE

69.7%

0.069

Disease-free survival

 Study region

  China

4

1.562

1.047–2.332

0.029

RE

89.6%

0.526

  Japan

2

1.838

1.373–2.461

 < 0.001

RE

0.0%

 < 0.001

  Korea

1

1.456

0.812–2.604

0.206

-

-

-

 Sample size

   ≤ 300

3

1.385

0.859–2.233

0.182

RE

76.4%

0.014

   > 300

4

1.783

1.369–2.322

0.000

RE

52.2%

0.099

 Cut-off

   > 30

1

2.130

1.240–3.659

0.006

-

-

-

   ≤ 30

5

1.540

1.081–2.193

0.017

RE

86.8%

 < 0.001

  Other

1

1.730

1.223–2.447

0.002

-

-

-

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BMC Cancer

ISSN: 1471-2407

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