Table 4 Treatment-related adverse events
Adverse events | Any grade | Grade 1 | Grade 2 | Grade 3 | Grade 4 |
|---|---|---|---|---|---|
Hematologic | Â | Â | Â | Â | Â |
 Anemia | 23(10.9) | 14(6.6) | 7(3.3) | 1(0.5) | 1(0.5) |
 Leukopenia | 151(71.6) | 15(7.1) | 87(41.2) | 47(22.3) | 2(0.9) |
 Neutropenia | 141(66.8) | 18(8.5) | 46(21.8) | 57(27.0) | 20(9.5) |
 Thrombocytopenia | 30(14.2) | 11(5.2) | 14(6.6) | 3(1.4) | 2(0.9) |
Non-hematologic | Â | Â | Â | Â | Â |
 Nausea/vomiting | 10(4.7) | 10(4.7) | - | - | - |
 Diarrhoea | 4(1.9) | 3(1.4) | 1(0.5) | - | - |
 Anorexia | 6(2.8) | 5(2.4) | 1(0.5) | - | - |
 Dry eyes/Blurred vision | 3(1.4) | 3(1.4) | - | - | - |
 Skin rash | 6(2.8) | 6(2.8) | - | - | - |
 Mucositis | 8(3.8) | 8(3.8) | - | - | - |
 Alopecia | 11(5.2) | 11(5.2) | - | - | - |
 Fatigue | 23(10.9) | 19(9.0) | 4(1.9) | - | - |
Blood biochemical | Â | Â | Â | Â | Â |
 Elevated TBIL | 4(1.9) | 1(0.5) | 1(0.5) | - | 2(0.9) |
 Elevated ALT/AST | 10(4.7) | 6(2.8) | 1(0.5) | 1(0.5) | 2(0.9) |
 Decreased ALB | 1(0.5) | - | - | 1(0.5) | - |