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Table 2 Prior therapy for early breast cancer and metastatic breast cancer

From: Palbociclib plus endocrine therapy in hormone receptor-positive and HER2 negative metastatic breast cancer: a multicenter real-world study in the northwest of China

Prior therapy for EBC

All patients(n = 211)

1st line(n = 85)

2nd line(n = 78)

≥ 3rd line(n = 48)

 Neoadjuvant CHT

36(17.1)

17(20.0)

14(17.9)

5(10.4)

 Surgery

173(82.0)

62(72.9)

69(88.5)

42(87.5)

 Adjuvant CHT

139(65.9)

51(60)

49(62.8)

39(81.3)

 Adjuvant RT

98(46.4)

37(43.5)

35(44.9)

26(54.2)

 Adjuvant ET

128(60.7)

45(52.9)

48(62.8)

34(70.8)

  SERM

66(51.6)

22(47.8)

25(52.1)

19(55.9)

  AI

62(48.4)

24(52.2)

23(47.9)

15(44.1)

   Letrozole

35(27.3)

13(28.3)

10(20.8)

12(35.2)

   Anatrozole

5(3.9)

2(4.3)

1(2.2)

2(5.9)

   Exemestane

13(10.2)

4(8.7)

8(16.7)

1(2.9)

   NA

9(7.0)

5(10.9)

4(8.7)

-

Prior therapy for MBC

    

 Prior CHT for MBC

82(38.9)

7(8.2)

38(48.7)

37(77.1)

 Prior ET for MBC

63(29.9)

-

30(38.5)

33(68.8)

  SERM

4(6.3)

-

3(10.0)

1(3.0)

  AI

22(34.9)

-

12(40.0)

10(30.3)

  SERD

37(58.7)

-

15(50.0)

22(66.7)

  1. Values are presented as number (%) unless otherwise indicated. EBC, Early breast cancer; CHT, Chemotherapy; RT, Radiation therapy; ET, Endocrine therapy; SERM, Selective estrogen receptor modulators; AI, Aromatase inhibitors; MBC, Metastatic breast cancer; SERD, Selective estrogen receptor degrader