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Table 2 Quality of the first surgery and second resection in AYA patients treated in RSC and non-RSC.

From: Management and outcomes of adolescent and young adult sarcoma patients: results from the French nationwide database NETSARC

 

Patients with first surgery*

 
 

AYA in RSC ( n  = 1,290)

AYA in non-RSC ( n  = 937)

Comparison of AYA in RSC and in non-RSC (p-value)

Patient management

   

  Pre-treatment biopsy a

1102 (86%)

447 (48%)

< 0.001

  Pre-treatment imaging

1120 (87%)

529 (57%)

< 0.001

  Neoadjuvant treatment b

486 (57%)

81 (14%)

< 0.001

Diagnosis and surgery with identical dates

226 (18%)

634 (68%)

< 0.001

First surgery c

  

0.120

  Curetage

15 (1%)

5 (0%)

 

  Tumor resection

1275 (99%)

932 (99%)

 

Quality of first surgery *

  

< 0.001

  No margin

56 (4%)

26 (3%)

 

  R0 margins

735 (58%)

188 (20%)

 

  R1 margins

225 (18%)

254 (27%)

 

  R2 margins

48 (4%)

170 (18%)

 

  Unknown margins

211 (17%)

294 (31%)

 

Patients reoperated (second resection) c

79 (9%)

271 (40%)

< 0.001

  Reoperation in patients with initial R1 margins d

43 (24%)

113 (56%)

< 0.001

  Reoperation in patients with initial R2 margins e

15 (44%)

94 (64%)

0.029

Hospital/cancer center for second resection

  

< 0.001

  RSC

55 (70%)

131 (48%)

 

  non-RSC

5 (6%)

85 (31%)

 

  Unknown

19 (24%)

55 (20%)

 
  1. *excluding curetage
  2. Diagnosis and surgery with identical dates also described as “whoops surgery”. “No margin” qualification issued from pathology description. “Unknown margins” indicates that margin status was not mentioned in pathology report. Missing data: a n = 14; bn = 774; cn = 642 dn = 100; en = 38