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Table 2 LASSO-penalized multivariable Cox analysis before PSM

From: Is prior cancer history a hindrance for non-small cell lung cancer patients to participate in clinical trials?

Characteristic

OSa

DFSb

HR

95% CI

P

HR

95% CI

P

Age, years

  

 < 0.001

   

 Continue

1.042

1.0314–1.050

    

BMI

  

 < 0.001

   

 Continue

0.953

0.931–0.976

    

Histology

  

 < 0.001

  

0.001

 ADC

1

  

1

  

 SCC

1.231

1.037–1.462

 

1.143

0.978–1.336

 

 Other

1.751

1.328–2.309

 

1.574

1.223–2.025

 

Pathologic TNM stage

  

 < 0.001

  

 < 0.001

 I

1

  

1

  

 II

3.110

2.533–3.819

 

3.248

2.703–3.904

 

 III

5.564

4.672–6.626

 

6.029

5.139–7.073

 

Postoperative complication

  

0.292

   

 Without

1

     

 With

1.167

0.876–1.554

    

LVI

     

 < 0.001

 Without

   

1

  

 With

   

1.335

1.138–1.567

 
  1. LASSO least absolute shrinkage and selection operator, PSM propensity score matching, OS overall survival, DFS disease-free survival, BMI body mass index, ADC adenocarcinoma, SCC squamous cell carcinoma, TNM tumor-node-metastasis, LVI lymphovascular invasion
  2. a Age, BMI, histology, pathologic TNM stage and postoperative complication were included in the multivariable Cox analysis of OS before PSM
  3. b histology, pathologic TNM stage and LVI were included in the multivariable Cox analysis of DFS before PSM