Characteristics | with prior cancer (N = 338) | without prior cancer (N = 3,764) | P |
---|---|---|---|
Age, years | < 0.001a | ||
Median (range) | 60 (29–84) | 61 (18–86) | |
Sex | < 0.001 | ||
Male | 112 (33.1) | 1,957 (52.0) | |
Female | 226 (66.9) | 1,807 (48.0) | |
Smoking | < 0.001 | ||
Non-smoker | 252 (74.6) | 2,410 (64.0) | |
Smoker | 86 (25.4) | 1,354 (36.0) | |
Family tumor history | 0.023 | ||
Without | 289 (85.5) | 3,369 (89.5) | |
With | 49 (14.5) | 395 (10.5) | |
Preoperative comorbidity | 0.120 | ||
Without | 127 (37.6) | 1,578 (41.9) | |
With | 211 (62.4) | 2,186 (58.1) | |
BMI | 0.094a | ||
Median (range) | 24.1 (15.6–38.9) | 24.0 (14.3–44.8) | |
FEV1 (%) | 0.470a | ||
Median (range) | 95.9 (21.1–259.0) | 94.2 (52.6–165.0) | |
DLCO (%) | 0.003a | ||
Median (range) | 87.5 (11.6–160.8) | 83.7 (41.5–708.0) | |
Clinical T category | 0.007 | ||
1 | 285 (84.3) | 2,910 (77.3) | |
2 | 44 (13.0) | 589 (15.6) | |
3 | 6 (1.8) | 173 (4.6) | |
4 | 3 (0.9) | 92 (2.4) | |
Clinical N category | 0.048 | ||
0 | 309 (91.4) | 3,268 (86.8) | |
1 | 3 (0.9) | 69 (1.8) | |
2 | 26 (7.7) | 427 (11.3) | |
ASA grade | < 0.001b | ||
1 | 36 (10.7) | 758 (20.1) | |
2 | 291 (86.1) | 2,840 (75.5) | |
3 | 11 (3.3) | 162 (4.3) | |
4 | 0 (0.0) | 4 (0.1) | |
Surgical approach | 0.005 | ||
VATS | 315 (93.2) | 3,317 (88.1) | |
Open | 23 (6.8) | 447 (11.9) | |
Surgical extent | 0.011 | ||
Lobectomy | 230 (68.0) | 2,769 (73.6) | |
Sublobectomy | 104 (30.8) | 904 (24.0) | |
Pneumonectomy | 4 (1.2) | 91 (2.4) | |
Tumor location | 0.521 | ||
Right upper lobe | 119 (35.2) | 1,193 (31.7) | |
Right middle lobe | 18 (5.3) | 241 (6.4) | |
Right lower lobe | 61 (18.0) | 784 (20.8) | |
Left upper lobe | 92 (27.2) | 981 (26.1) | |
Left lower lobe | 48 (14.2) | 565 (15.0) | |
Histology | 0.364 | ||
ADC | 282 (83.4) | 3,020 (80.2) | |
SCC | 45 (13.3) | 596 (15.8) | |
Other | 11 (3.3) | 148 (3.9) | |
VPI | 0.310 | ||
Without | 271 (80.2) | 2,928 (77.8) | |
With | 67 (19.8) | 836 (22.2) | |
LVI | 0.062 | ||
Without | 299 (88.5) | 3,187 (84.7) | |
With | 39 (11.5) | 577 (15.3) | |
Tumor size, cm | 0.005 | ||
Continue | 1.8 (0.1–14.0) | 1.5 (0.4–13.0) | |
Pathologic T category | 0.006 | ||
1 | 228 (67.5) | 2,235 (59.4) | |
2 | 93 (27.5) | 1,165 (31.0) | |
3 | 10 (3.0) | 255 (6.8) | |
4 | 7 (2.1) | 109 (2.9) | |
Pathologic N category | 0.138 | ||
0 | 284 (84.0) | 2,992 (79.5) | |
1 | 21 (6.2) | 302 (8.0) | |
2 | 33 (9.8) | 470 (12.5) | |
Pathologic TNM stage | 0.004 | ||
I | 269 (79.6)) | 2,697 (71.7) | |
II | 26 (7.7) | 486 (12.9) | |
III | 43 (12.7) | 581 (15.4) | |
Postoperative complications | 0.142 | ||
Without | 317 (93.8) | 3,596 (95.5) | |
With | 21 (6.2) | 168 (4.5) | |
Adjuvant therapy | 0.003 | ||
No | 270 (79.9) | 2,721 (72.3) | |
Yes | 68 (20.1) | 1,043 (27.7) | |
Hospital stay, day | 0.668a | ||
Continue | 12 (2–61) | 12 (2–99) |