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Fig. 2 | BMC Cancer

Fig. 2

From: Enhancement of radiation therapy by indoleamine 2,3 dioxygenase 1 inhibition through multimodal mechanisms

Fig. 2

Effects of IDO1 inhibition on the proliferation of colorectal cancer cells in vitro. Inhibition by gene silencing of IDO1 in HCT116 (a) and HT-29 cells (b). Inhibition by 1-methyl tryptophan (1-MT) in HCT116 cells (c,d), HT-29 (e) and Colon26 (f). Results after 48-h treatment are shown as absorbances measured at 490 nm by the MTS assay. Concentration of siRNA,10 nM; concentration of kynurenine (Kyn), 100 µM. Bars indicate standard deviations. * p < 0.001

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