Table 3 Effect on hepatic mRNA expresion of cancer related genes using RNA-seq analysis
Sr.no | Gene symbol | Normal control Vs Disease control log2 Fold Change | Disease control Vs D-Saro (3 mg/kg) log2 Fold Change | Reference link for significance of genes in HCC |
|---|---|---|---|---|
1 | Cdc20 | 3.25 | -1 | https://www.spandidos-publications.com/10.3892/mmr.2021.12122 |
2 | Hmmr | 3.15 | -1 | |
3 | Tpx2 | 3.05 | -1 | |
4 | Cenpf | 2.91 | −1.1 | https://www.frontiersin.org/articles/10.3389/fonc.2021.738841/full |
5 | Birc5 | 2.45 | −1.5 | https://bmccancer.biomedcentral.com/articles/10.1186/s12885-021-08390-7 |
6 | Ube2c | 2.17 | −1.2 | |
7 | Foxm1 | 2.1 | −1.3 | |
8 | Pold4 | 1.46 | −1.1 | |
9 | Nup210 | 1.39 | −1.1 | |
10 | Prkcb | 1.38 | −1.2 | |
11 | Cenpm | 1.3 | −1.9 | https://jeccr.biomedcentral.com/articles/10.1186/s13046-019-1444-0 |
12 | Orc1 | 1.25 | −1.1 |