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Fig. 4 | BMC Cancer

Fig. 4

From: Saroglitazar suppresses the hepatocellular carcinoma induced by intraperitoneal injection of diethylnitrosamine in C57BL/6 mice fed on choline deficient, l-amino acid- defined, high-fat diet

Fig. 4

Effect of 27 weeks treatment with saroglitazar on hepatic mRNA levels. Heatmap of liver transcriptomic profile using next-generation sequencing (NGS). Genes that had a p-value adjusted (padj) value < 0.05 were considered as significant results in the differential expression analysis. Those genes which were found to have log2 (fold-change) ≤ − 1 or log2(fold-change) ≥ 1 among the significant results, were considered to be significantly down-regulated or up-regulated respectively

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