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Table 5 Factors influencing postoperative survival

From: Normalization of tumor markers and a clear resection margin affect progression-free survival of patients with unresectable pancreatic cancer who have undergone conversion surgery

 

Postoperative PFS

Postoperative OS

 

Univariate analysis

Multivariate analysis

Univariate analysis

Multivariate analysis

 

P

P

HR

95%CI

P

P

HR

95%CI

Age (> 60 vs. ≤ 60 years)

0.307

-

-

-

0.81

-

-

-

Sex (male vs. female)

0.280

-

-

-

0.262

-

-

-

Location of pancreatic tumor (proximal vs. distal)

0.732

-

-

-

0.337

-

-

-

Tumor diameter (< 20 vs. ≥ 20 mm)

0.165

-

-

-

0.313

-

-

-

Margin (R0 vs. R1 and R2)

 < 0.001

 < 0.001

0.194

0.088–0.426

0.102

-

-

-

LN metastasis (( +) vs. ( −))

0.884

-

-

-

0.058

-

-

-

RECIST (PR and CR vs. SD)

0.306

-

-

-

0.016

0.079

0.399

0.143–1.114

Duration of systemic treatment

0.094

-

-

-

0.08

-

-

-

TNM staging (0, I and II vs. III and IV)

0.686

-

-

-

0.686

-

-

-

UPC (LAPC vs. MPC)

0.949

-

-

-

0.414

-

-

-

Postoperative change in CA19-9/CEA level

(decrease to normal vs. not normalized)

0.001

0.001

0.253

0.114–0.560

0.013

0.071

0.405

0.152–1.108

CAP grading system (0 and 1 vs. 2 and 3)

0.589

-

-

-

0.834

-

-

-