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Fig. 4 | BMC Cancer

Fig. 4

From: Notch3 signaling promotes colorectal tumor growth by enhancing immunosuppressive cells infiltration in the microenvironment

Fig. 4

Interference Notch3 attenuate the colon tumor growth and decrease Macrophage infiltration in vivo. (a) Knockdown efficiency of Notch3-shRNA in MC38 cells. NTC, non-targeting control. (b) Colony formation assay of MC38 cells. (c) Spheroid formation assay of MC38 cells. (d) MC38 cells transfected with Notch3-shRNA or NTC were subcutaneous injected into C57BL/6 mice, represented tumors were show. (e) The proliferation curve of MC38 derived tumors. (f) The quantification of tumor weight. (g) Flow cytometry analyze of MC38 derived tumors. (h) The quantification of the results in g

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BMC Cancer

ISSN: 1471-2407

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