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Table 2 Sensitivity, specificity, PPV, NPV, and DOR values of 16 proteins in early-stage LUAD

From: Secreted proteins MDK, WFDC2, and CXCL14 as candidate biomarkers for early diagnosis of lung adenocarcinoma

 

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

DOR

MDK

80.77

100.00

100.00

68.75

∞

WFDC2

84.62

81.82

91.67

69.23

24.75

CXCL14

88.46

81.82

92.00

75.00

34.50

CXCL13

50.00

81.82

86.67

40.91

4.50

CEACAM1

69.23

9.09

64.29

11.11

0.23

COL1A1

30.77

100.00

100.00

37.93

∞

FAP

46.15

90.91

92.31

41.67

8.57

SDC1

50.00

100.00

100.00

45.83

∞

MMP12

53.85

90.91

93.33

45.45

11.67

TNC

69.23

81.82

90.00

52.94

10.13

THBS2

57.69

81.82

88.24

45.00

6.14

SPP1

96.15

27.27

75.76

75.00

9.38

MUC1

50.00

72.73

81.25

38.10

2.67

TK1

26.92

100.00

100.00

36.67

∞

PLAU

65.38

54.55

77.27

40.00

2.27

TIMP1

53.85

81.82

87.50

42.86

5.25

  1. Abbreviation: PPV positive predictive value, NPV negative predictive value, PPV positive predictive value, NPV negative predictive value, DOR Diagnostic Odds Ratio