No. of patients (%) | During NACT | During CCRT | During follow-up | ||
---|---|---|---|---|---|
Toxicity | Any Grade | Grade ≥ 3 | Any Grade | Grade ≥ 3 | Grade ≥ 3 |
Any hematological toxicity | 41 (82.0) | 20 (40.0) | 48 (96.0) | 26 (52.0) | 1 (2.0) |
Anemia | 18 (36.0) | 3 (6.0) | 38 (76.0) | 19 (38.0) | 1 (2.0) |
Neutropenia | 35 (70.0) | 18 (36.0) | 42 (84.0) | 12 (24.0) | 0 (0) |
Thrombocytopenia | 3 (6.0) | 0 (0) | 25 (50.0) | 8 (16.0) | 0 (0) |
Any non hematological toxicity | 49 (98.0) | 16 (32.0) | 43 (86.0) | 16 (32.0) | 1 (2.0) |
Nausea | 43 (86.0) | 4 (8.0) | 31 (62.0) | 7 (14.0) | 0 (0) |
Vomiting | 30 (60.0) | 6 (12.0) | 19 (38.0) | 1 (2.0) | 0 (0) |
Constipation | 14 (28.0) | 1 (2.0) | 12 (24.0) | 0 (0) | 0 (0) |
Diarrhea | 14 (28.0) | 3 (6.0) | 19 (38.0) | 4 (8.0) | 1 (2.0) |
Fatigue | 36 (72.0) | 7 (14.0) | 37 (74.0) | 10 (20.0) | 0 (0) |
Alopecia | 45 (90.0) | - | 36 (72.0) | - | - |
Anal pain | 0 (0) | 0 (0) | 18 (36.0) | 3 (6.0) | 1 (2.0) |
Peripheral Neuropathy | 3 (6.0) | 0 (0) | 15 (30.0) | 0 (0) | 0 (0) |
Creatinine Elevation | 1 (2.0) | 0 (0) | 10 (20.0) | 0 (0) | 0 (0) |
Hepatic Enzyme Elevation | 1 (2.0) | 1 (2.0) | 8 (16.0) | 2 (4.0) | 0 (0) |