Skip to main content

Table 2 Initial site of recurrence and outcomes of the patients who presented with disease recurrence during follow-up

From: Neoadjuvant chemotherapy with weekly cisplatin and paclitaxel followed by chemoradiation for locally advanced cervical cancer

No

Age

Histology

FIGO

Response to treatment

Recurrent and metastases

Treatment Compliance

Current situation

(y)

Stage

Post NACT

Post CCRT

PFS a

(m)

Region

(Reason)

OS a

(m)

1

66

SC

IIIC1r

SD

CR

31

Lymphatic metastases (para-aortic and left diaphragmatic foot)

/

Alive

(39)

2

54

SC

IIIC1r

SD

PD

7

Metastases in the lung and mesentery

Reduced cisplatin cycle concurrent with radiotherapy to 3 (hepatic insufficiency)

Dead

(12)

3

40

SC

IIIC1r

SD

PR

20

Metastases in the pelvis

/

Dead

(31)

4

53

SC

IIB

PR

CR

12

Lymphatic metastases (para-aortic and parailiac vascular)

Reduced NACT cycle to 3

(myelosuppression)

Discontinued brachytherapy

(grade 4 neutropenia that could not be improved)

Alive

(25)

5

35

SC

IIIC1r

SD

PD

6

Lymphatic metastases (left collarbone, para-aortic, parailiac vascular) and liver metastases

/

Dead

(10)

6

60

ASC

IIIC2r

CR

CR

13

Local recurrence and lymphatic metastases (para-aortic, pelvic and inguinal)

/

Alive

(19)

7

57

SC

IIIC1r

SD

PD

7

Metastases in the lung, mesentery and lymphonodus (inguinal)

Delayed beginning of chemoradiation

(grade 4 neutropenia with high fever)

Alive

(15)

8

66

SC

IIIC2r

PR

CR

10

Metastases in the vagina

/

Dead

(12)

9

43

SC

IIIC2r

SD

PD

6

Metastases in the lung and mesentery

Reduced cisplatin cycle concurrent with radiotherapy to 3 (thrombocytopenia)

Postponed brachytherapy for 2 weeks (a large amount of vaginal bleeding with severe anemia and thrombocytopenia)

Dead

(14)

10

50

SC

IIIC1r

PR

PD

6

Metastases in the vagina

Delayed beginning of chemoradiation

(grade 4 hepatic insufficiency)

Alive

(10)

  1. aThis time was calculated from the beginning of treatment
  2. SC squamous carcinoma, ASCadenosquamous carcinoma