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Fig. 9 | BMC Cancer

Fig. 9

From: Inference of core needle biopsy whole slide images requiring definitive therapy for prostate cancer

Fig. 9

A representative example of a case that had both indolent and aggressive prediction. These outputs were obtained on a whole slide image (WSI) from the core needle biopsy test set using the model (TL-Colon poorly ADC (x20, 512) and FS+WS). In (A), small, indistinct, or fused glands (Gleason pattern 4) adenocarcinoma was predominant; however, Gleason pattern 3 adenocarcinoma is mixed in various degrees (D, E). The boundary between Gleason patterns 3 and 4 adenocarcinoma was unclear and transitional (D, E). The heatmap image (B) shows indolent prediction, and (C) shows aggressive prediction. In both (D) and (E) areas, indolent (F, H) and aggressive (G, I) prediction outputs were overlapped. The model (TL-Colon poorly ADC (x20, 512) and FS+WS) predicted the WSI (A) as both indolent and aggressive. The heatmap uses the jet color map where blue indicates low probability and red indicates high probability

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