Table 1 Study endpoints

1.0 Primary endpoints

1.1 Local control at 12 months.

2.0 Secondary endpoints

2.1 Local control at 6 and 24 months

2.2 Distance brain recurrence rate (%) at 6,12, and 24 months

2.3 Leptomeningeal recurrence rate (%) at 6, 12, 24 months

2.4 Overall survival (in months) at 6, 12 and 24 months

2.5 Hopkins Verbal Learning Test Revised score (points) at 3, 6, 9, 12, 16, 24 months

2.6 Controlled Oral Word Association test score (points) at 3, 6, 9, 12, 16, 24 months

2.7 Trail Making Test score (points) at 3, 6, 9, 12, 16, 24 months