Table 3 Univariate and multivariate Cox proportional hazards analysis of MICAL1 expression and OS for patients with KIRC
Characteristics | Total (N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
Hazard ratio (95% CI) | p value | Hazard ratio (95% CI) | p value | ||
T stage (T2-T4 vs. T1) | 530 | 2.872 (2.063–3.998) | *** | 0.753 (0.402–1.409) | 0.375 |
M stage (M1 vs. M0) | 498 | 4.333 (3.170–5.922) | *** | 2.532 (1.737–3.689) | *** |
Age (> 60 vs. <=60) | 530 | 1.753 (1.290–2.383) | *** | 1.685 (1.231–2.306) | ** |
Gender (Male vs. Female) | 530 | 1.052 (0.771–1.434) | 0.750 |  |  |
Histologic grade (G3-G4 vs. G1-G2) | 522 | 2.660 (1.888–3.748) | *** | 1.677 (1.156–2.434) | ** |
Pathologic stage (Stage III- IV vs. Stage I- II) | 527 | 3.860 (2.809–5.305) | *** | 2.354 (1.254–4.418) | ** |
MICAL1 (High vs. Low) | 530 | 1.686 (1.243–2.287) | *** | 1.536 (1.124–2.100) | ** |