Table 1 Chi-square/Fisher’s exact/Wilcoxon test of clinical variables against the patient clusters PG0 and PG1

N

42

36

Sex

Female

4

10

0.043

*

Male

38

26

Ethnicity

Chinese

31

20

0.363

Filipino

3

1

Indian

1

2

Indonesian

1

1

Malay

2

2

Thai

2

7

Others

2

3

Significant Alcohol Consumption

Yes

11

9

0.683

No

23

17

Unknown

8

10

Child's Pugh score

A

41

36

1.000

B

1

0

Diabetes

Yes

17

12

0.636

No

25

24

Tumour Multiplicity

Yes

7

8

0.588

No

35

28

Fibrosis Stage

0

14

6

0.010^*

**

1

3

4

2

1

9

3

11

4

4

9

11

Microvascular Invasion

Yes

12

17

0.110

No

30

19

Edmondson Grade

1

5

2

0.058

2

26

15

3

11

17

4

0

2

Steatosis

0–5%

20

23

0.268

5–33%

14

11

33–66%

3

0

Overall Survival

Alive

36

25

0.110

Dead

6

11

Tumour Stage TNM V8

I

25

17

0.216

II

13

10

III

4

9

Recurrence status

Yes

24

14

0.125

No

18

22

HBV Status

positive

23

29

0.030

*

negative

19

7

HCV Status

positive

4

2

0.681

negative

38

34

Max. Tumour Diameter (cm)

6.84 ± 4.94

6.35 ± 3.93

0.876

Albumin (g/L)

40.95 ± 4.32

41.3 ± 3.55

0.751

Bilirubin (umol/L)

13.73 ± 4.57

13.12 ± 5.68

0.348

AST (U/L)

50.65 ± 36.2

50.23 ± 52.29

0.854

ALT (U/L)

50.47 ± 53.97

33.86 ± 19.92

0.196

Alkaline Phosphatase (U/L)

108.85 ± 53.44

125.41 ± 121.7

0.943

Prothrombin Time (secs)

10.91 ± 0.96

11.55 ± 1.35

0.025

*

Platelets (× 10^9)

232.82 ± 89.59

239.14 ± 71.48

0.344

AFP (ng/ml)

1925.1 ± 9012.17

4362.23 ± 11,826.79

0.023

*

Recurrence-free survival days

675.76 ± 462.37

521.72 ± 433.32

0.132