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Table 2 Procedural Characteristics (Per-Patient Analysis)

From: Effect of chlorhexidine mouthrinse on prevention of microbial contamination during EBUS-TBNA: a randomized controlled trial

 

Chlorhexidine Mouthrinse

(n = 51)

Usual Care

(n = 55)

P Value

Indication for EBUS-TBNA

> 0.99

 Diagnosis or staging of malignancy

49 (96.1)

52 (94.5)

 

 Diagnosis of benign disease

2 (3.9)

3 (5.5)

 

Conventional bronchoscopy

42 (82.4)

49 (89.1)

0.32

 Bronchial washing

6 (11.8)

5 (9.1)

0.65

 Bronchoalveolar lavage

0 (0.0)

1 (1.8)

> 0.99

 Endobronchial biopsy

8 (15.7)

3 (5.5)

0.08

EUS-B-FNA

4 (7.8)

5 (9.1)

> 0.99

Number of insertions of EBUS bronchoscope

0.50

  ≤ 1

45 (88.2)

46 (83.6)

 

  > 1

6 (11.8)

9 (16.4)

 

Number of aspiration needles used per patient

0.28

  ≤ 1

44 (86.3)

51 (92.7)

 

  > 1

7 (13.7)

4 (7.3)

 

Number of LNs punctured per patient

0.91

  ≤ 3

31 (60.8)

34 (61.8)

 

  > 3

20 (39.2)

21 (38.2)

 

Total number of aspirations per patient

0.89

  ≤ 5

29 (56.9)

32 (58.2)

 

  > 5

22 (43.1)

23 (41.8)

 

Characteristics of LNs/masses

 

 Heterogeneous echogenicity on ultrasound

22 (43.1)

16 (29.1)

0.13

 Coagulation necrosis sign on ultrasound or aspirates with pus-like material

10 (19.6)

3 (5.5)

0.03

Procedure time

 

 Conventional bronchoscopy, min

3 (2–6)

3 (2–5)

0.56

 EBUS-TBNA, min

19 (9–30)

20 (14–31)

0.37

Dosage of sedatives

 

 Midazolam, mg

4 (3–5)

5 (3–5)

0.37

 Fentanyl, μg

50 (50–50)

50 (50–50)

0.49

Antibiotic prophylaxis after EBUS-TBNA

19 (37.3)

19 (34.5)

0.77

  1. Data are presented as number (%) or median (interquartile range). EBUS Endobronchial ultrasound, EBUS-TBNA EBUS-guided transbronchial needle aspiration, EUS-B-FNA Transesophageal bronchoscopic ultrasound-guided fine-needle aspiration, LN Lymph node