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Table 1 Reclassification of breast cancers into molecular subtype

From: Long term trends of breast cancer incidence according to proliferation status

Molecular subtype

Molecular marker

Luminal A

ER+ and/or PR+, HER2, Ki-67 < 15%

Luminal B (HER2)

ER+ and/or PR+, HER2, Ki-67 ≥ 15%

Luminal B (HER2+)

ER+ and/or PR+, HER2+

HER2 type

ER, PR, HER2+

Basal phenotype

ER, PR, HER2, CK5+ and/or EGFR+

5 negative phenotype

ER, PR, HER2, CK5, EGFR

  1. Abbreviations: ER oestrogen receptor, PR progesterone receptor, HER2 human epidermal growth factor receptor 2, CK5 cytokeratin 5, EGFR epidermal growth factor receptor