Training cohort (n = 226) | Validation cohort (n = 118) | P value | ||
---|---|---|---|---|
OR (95% CI) | OR (95% CI) | |||
Mitosis | 3.202 (1.650–6.214) | 0.0006 | 4.927 (2.353–7.856) | 0.0013 |
MELF pattern | ||||
Absent | 1 | 1 | ||
Present | 1.977 (0.508–7.695) | 0.056 | 1.689 (0.938–9.100) | 0.325 |
LVI | ||||
Absent | 1 | 1 | ||
Present | 2.650 (1.121–6.262) | 0.0263 | 4.912 (0.833–8.951) | 0.078 |
Necrosis | ||||
Absent | 1 | 1 | ||
Present | 1.142 (0.307–4.244) | 0.842 | 1.147 (0.186–7.052) | 0.881 |
High-grade pattern | 1.217 (1.065–1.389) | 0.0037 | 1.795 (1.317–2.446) | < 0.001 |