Variable | Univariate analysis | Multi-variate analysis | ||||
---|---|---|---|---|---|---|
 | Odds ratio | 95% CI | p-value | Odds ratio | 95% CI | P value |
Age | 0.852 | 0.733–0.999 | 0.036 | 0.993 | 0.975–1.011 | 0.435 |
CEA | 1.282 | 1.188–1.384 |  < 0.001 | 1.085 | 1.001–1.079 | 0.046 |
CA125 | 1.057 | 1.036–1.078 |  < 0.001 | 1.052 | 1.027–1.077 |  < 0.001 |
CA153 | 1.124 | 1.094–1.154 |  < 0.001 | 1.073 | 1.042–1.105 |  < 0.001 |
Tumor size | 1.313 | 1.168–1.475 |  < 0.001 | 1.145 | 1.009–1.299 | 0.036 |
Location | ||||||
 UOQ | Reference |  |  |  | ||
 LOQ | 0.605 | 0.327–1.118 | 0.109 |  |  |  |
 LIQ | 0.706 | 0.398–1.254 | 0.236 |  |  |  |
 UIQ | 0.659 | 0.395–1.099 | 0.110 |  |  |  |
 Central | 0.398 | 0.128–1.241 | 0.112 |  |  |  |
Vascular-invasion | ||||||
 No | Reference | Reference | ||||
 Yes | 10.848 | 6.652–17.690 |  < 0.001 | 7.736 | 3.903–15.332 |  < 0.001 |
Calcification | ||||||
 No | Reference | Reference | ||||
 Yes | 1.900 | 1.325–2.271 |  < 0.001 | 1.650 | 1.082–2.514 | 0.02 |
Tumor grade | ||||||
 Well differentiated, grade 1 | Reference |  |  |  | ||
 Moderately differentiated, grade 2 | 4.362 | 1.775–10.718 | 0.001 | 5.338 | 1.514–18.840 | 0.009 |
 Poorly differentiated, grade 3 | 5.657 | 2.318–13.804 |  < 0.001 | 5.864 | 1.670–20.594 | 0.006 |
Histology subtype | ||||||
 Invasive ductal carcinoma | Reference |  |  |  | ||
 Invasive lobular carcinoma | 1.838 | 0.755–4.477 | 0.180 |  |  |  |
 Mixed | 2.056 | 0.964–4.379 | 0.062 |  |  |  |
 Other | 0.503 | 0.215–4.379 | 0.113 |  |  |  |
ER status | ||||||
 Negative | 0.693 | 0.447–1.073 | 0.101 |  |  |  |
 Positive | Reference |  |  |  | ||
PR status | ||||||
 Negative | 0.680 | 0.469–0.986 | 0.045 |  |  |  |
 Positive | Reference |  |  |  | ||
 KI67 | 1.006 | 0.998–1.014 | 0.117 |  |  |  |
Her-2 status | ||||||
 Negative | 0.920 | 0.626–1.352 | 0.673 |  |  |  |
 Positive | Reference |  |  |  | ||
Biological subtype | ||||||
 Luminal A | 1.147 | 0.532–2.474 | 0.726 |  |  |  |
 Luminal B | 1.932 | 1.046–3.567 | 0.035 |  |  |  |
 Her-2 positive | 1.554 | 0.706–3.421 | 0.273 |  |  |  |
 TNBC | Reference |  |  |  |