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Fig. 6 | BMC Cancer

Fig. 6

From: Autophagy inhibition and reactive oxygen species elimination by acetyl-CoA acetyltransferase 1 through fused in sarcoma protein to promote prostate cancer

Fig. 6

ACAT1 plays a tumor-promoting role through FUS. A and B. After a simultaneous increase in the expression of ACAT1 and FUS, the expression of the related proteins changed in (A) LNCaP and (B) PC3 cells. The statistical analysis of gray values is shown. *P < 0.05, **P < 0.01. C After a simultaneous increase in the expression of ACAT1 and FUS, the accumulation of ROS is shown. LNCaP on the top and PC3 on the bottom. *P < 0.05, **P < 0.01. D and E. Edu assay, after a simultaneous increase in the expression of ACAT1 and FUS,the change of (D) LNCaP and (E) PC3 cells proliferation ability *P < 0.05, **P < 0.01. F and G. Transwell cell migration assay, after a simultaneous increase in the expression of ACAT1 and FUS,changes in the migration ability of (F) LNCaP cells and (G)PC3 cells .*P < 0.05, **P < 0.01

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BMC Cancer

ISSN: 1471-2407

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