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Fig. 1 | BMC Cancer

Fig. 1

From: Autophagy inhibition and reactive oxygen species elimination by acetyl-CoA acetyltransferase 1 through fused in sarcoma protein to promote prostate cancer

Fig. 1

High expression of ACAT1 in prostate cancer cells correlates with the tumor Gleason score. A and B. From the GEPIA database, the results show that in prostate adenocarcinoma (PRAD), the expression of ACAT1 is significantly higher than that in the adjacent normal tissues (T on the left, N on the right). C. Expression of ACAT1 in prostate tissue sections. (a) Normal prostate gland. (b) Prostate cancer tissue with a Gleason score of 3. (c) Prostate cancer tissue with a Gleason score of 4. (d) Prostate cancer tissue with a Gleason score of 5. D. From the Human Protein Atlas, display of ACAT1 expression in prostate cancer cell lines. E. From the GEPIA database, the results show that in prostate cancer, high expression of ACAT1 is associated with a poor prognosis. F. Tumorigenic ability of PC3 cell line with stable and high expression of ACAT1 in nude mice compared with that in the negative control group (P = 0.0206)

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BMC Cancer

ISSN: 1471-2407

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