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Table 2 KEGG pathway analysis of DEGs related with CRA

From: Identification and clinical validation of key genes as the potential biomarkers in colorectal adenoma

ONTOLOGY

ID

Description

P value

p.adjust

geneID

Count

Upregulated DEGs

  KEGG

hsa04310

Wnt signaling pathway

0.00033949

0.04854661

MMP7/PLCB4/AXIN2/LGR5/PLCB1/NKD1

6

  KEGG

hsa04918

Thyroid hormone synthesis

0.00098001

0.07007047

PLCB4/PLCB1/DUOX2/DUOXA2

4

Downregulated DEGs

  KEGG

hsa00910

Nitrogen metabolism

0.0001264

0.01579962

CA1/CA2/CA7

3

  KEGG

hsa00140

Steroid hormone biosynthesis

0.00044716

0.0279477

HSD11B2/HSD17B2/UGT2B15/DHRS11

4

  KEGG

hsa00380

Tryptophan metabolism

0.00192267

0.08011124

ACAT1/MAOA/TPH1

3