Fig. 8

Screening and verification of the hub genes by RT-qPCR. A-D The relative expression of REG1A, CA2 and HSD11B2 between colorectal mucosa and adenoma were measured by RT-qPCR (p-value < 0.01). TIMP1 had no significant difference. E ROC curve with corresponding AUC value for hub genes when classifying CRA from mucosa. *** indicates p-value < 0.001, ** indicates p-value < 0.01, NS, none significance