Fig. 11

Risk score analysis and Kaplan–Meier (KM) survival curves for COAD with high and low CA2 and HSD11B2 mRNA expression in GEPIA. A-B CA2 and HSD11B2 expression levols in COAD according to TCGA database. T, tumor; N, normal. The number of tumors was 275, and the number of normal tissues was 41. C Construction of the core genes risk score analysis in the TCGA dataset (clinical characteristics of 330 patients) including risk score, survival time and gene expression. D-E KM survival curves for overall survival (p-value = 0.021) and disease free survival (p-value = 0.16) in COAD according to CA2 expression. (F-G) KM survival curves for overall survival (p-value = 0.69) and disease free survival (p-value = 0.022) in COAD according to HSD11B2 expression. COAD, colon adenocarcinoma. * indicate p-value < 0.05. HR: hazard ratios. The dotted line as the 95% CI