Table 4 Associations between dementia status and all-cause mortality within 3 years of cancer diagnosis in older adults

Dementia

  No dementia

Reference

Reference

Reference

  Mild dementia

1.85 (1.54–2.22)

< 0.001

1.97 (1.65–2.34)

< 0.001

1.80 (1.54–2.10)

< 0.001

  Moderate-to-severe dementia

3.17 (2.43–4.12)

< 0.001

3.60 (2.83–4.59)

< 0.001

2.57 (2.00–3.30)

< 0.001

Age, years

  65–69

Reference

Reference

Reference

  70–74

1.14 (0.99–1.31)

0.060

1.18 (1.01–1.38)

0.042

1.18 (1.05–1.32)

0.004

  75–79

1.51 (1.31–1.73)

< 0.001

1.55 (1.33–1.80)

< 0.001

1.39 (1.24–1.56)

< 0.001

  80–84

2.28 (1.97–2.63)

< 0.001

2.12 (1.80–2.49)

< 0.001

2.18 (1.92–2.46)

< 0.001

  ≥ 85

2.96 (2.50–3.49)

< 0.001

3.41 (2.87–4.05)

< 0.001

2.85 (2.43–3.35)

< 0.001

Sex

  Female

Reference

Reference

Reference

  Male

1.17 (1.06–1.29)

0.002

1.26 (1.14–1.39)

< 0.001

1.76 (1.61–1.92)

< 0.001

Comorbidity

  No comorbidity

Reference

Reference

Reference

  Moderate comorbidities

1.49 (1.35–1.65)

< 0.001

1.58 (1.41–1.76)

< 0.001

1.18 (1.08–1.29)

< 0.001

  Severe comorbidities

1.91 (1.54–2.37)

< 0.001

2.82 (2.22–3.58)

< 0.001

1.45 (1.21–1.73)

< 0.001

Cancer stage

  0

—

0.77 (0.62–0.96)

0.021

—

  I

Reference

Reference

Reference

  II

2.55 (2.15–3.01)

< 0.001

1.24 (1.01–1.51)

0.037

2.62 (2.17–3.15)

< 0.001

  III

5.37 (4.67–6.17)

< 0.001

2.16 (1.80–2.60)

< 0.001

5.29 (4.58–6.11)

< 0.001

  IV

19.01 (16.95–21.31)

< 0.001

12.44 (10.50–14.75)

< 0.001

11.38 (9.98–12.97)

< 0.001

  Unstaged

11.50 (8.99–14.72)

< 0.001

10.83 (7.76–15.10)

< 0.001

10.03 (7.63–13.18)

< 0.001

Histology

  Non-small cell lung cancer

—

—

Reference

  Small cell lung cancer

—

—

1.25 (1.12–1.40)

< 0.001