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Table 1 Correlation coefficients of immunohistochemical biomarkers

From: Markers associated with genomic instability, immunogenicity and immune therapy responsiveness in Metaplastic carcinoma of the breast: Expression of γH2AX, pRPA2, P53, PD-L1 and tumor infiltrating lymphocytes in 76 cases

 

gH2AX

RPA2

tcPD-L1

icPD-L1

sTIL

RPA2

0.530

(p < 0.0005)

    

tcPD-L1

-0.045*

-0.085*

   

icPD-L1

-0.157

(p = 0.034)

-0.124*

0.453

(p = 0.001)

  

sTIL

0.051*

-0.059*

0.199*

0.453

(p < 0.0005)

 

iTIL

0.094*

0.076*

0.295

(p = 0.007)

0.007*

0.041*

  1. sTIL % stromal tumor-infiltrating lymphocytes, iTIL % intratumoral tumor-infiltrating lymphocytes, tcPD-L1% tumor cell-PD-L1, icPD-L1% immune cell PD-L1
  2. *non-significant p-values